Brain Slice Probe

The Brain Slice Probe* is one of the newest additions to Plexon’s family of specialty electrodes, probes and arrays. This amazing product is a multi-site, linear electrode array designed to capture neural activity from a tissue slice when positioned across the slice’s surface, then advanced into the tissue.

The tip of the Brain Slice Probe is fabricated by embedding individual electrode wires within bio-compatible, non-toxic epoxy. The comb-like construction of the tip is curved to enable viewing of the tip with a microscope while advancing the probe into tissue.

The Brain Slice Probe can be held with standard stereotaxic manipulators. Flexibility in the manufacturing process allows for different electrode sizes and spacing. In addition, it offers optional fluid delivery channels for precise drug delivery and fiber optic lines for optogenetic stimulation intermixed within the recording sites. The precise linear arrangement of the electrode sites enables current source density analysis of the field potential signals as recorded from laminar neural structures.

The platinum/iridium electrode recording sites are available in 15, 20, 25 and 40µm diameter options. The small electrode site diameter (15µm) enables effective single-unit recording, while a unique etching process of the electrode surface results in lowered impedances without significantly changing the overall surface area of the exposed recording site. The result is a small site suitable for resolving single units coupled with low impedance for a better single-to-noise ratio.

Brain Slice Probes are expertly handcrafted and made to order, typically a six-week manufacturing lead time for standard specifications. Your Plexon Sales Engineer is available to provide additional information and help you determine the most advantageous Brain Slice Probe configuration.