Plexon U-Probe

U-Probes* are Plexon’s most popular and fastest growing product in the electrodes, probes and arrays category.  They are exceptionally customizable and robust, multi-use, multi-site linear electrodes most often used for acute recordings in medium to large animals.

Flexibility in the manufacturing process allows for different electrode site arrangements and spacing, as well as optional fluid delivery channels for precise drug delivery or fiber optic lines for optogenetic stimulation intermixed within the recording sites. The precise linear arrangement of the electrode sites enables current source density analysis of the field potential signals as recorded from laminar neural structures.

The platinum/iridium electrode recording sites are available in 15, 20, 25 and 40µm diameter options. The small electrode site diameter (15µm) enables effective single-unit recording, while a unique etching process of the electrode surface results in lowered impedances without significantly changing the overall surface area of the exposed recording site. The result is a small site suitable for resolving single units coupled with low impedance for a better single-to-noise ratio.

U-Probes are conveniently available in single, stereotrode and tetrode configurations, each with a choice of 8, 16, 24, or 32 channels. The 8 channel, single configuration is the most popular option; however, some researchers find the 16, 24, and 32 channel stereotrodes and tetrodes to be especially effective for use in areas with an especially high density of neurons as found in the hippocampus.

Below are all three 16 channel configurations illustrated with four fluid capillaries or optic fibers:

U-Probes are well known for their robustness due in part to their stainless steel construction (as opposed to silicon), and ability to penetrate deep within the brain. When used according to proper procedures, U-Probes will support many penetrations through the dura over a long period of time.

You may also wish to explore other options in Plexon’s family of specialty electrodes, probes and arrays including our V-Probes, Thumbtack Probe or the Floating Microelectrode Array (FMA), the latter two for chronic use.

U-Probes are Plexon’s most popular and fastest growing product in the electrodes, probes and arrays category. U-Probes are expertly handcrafted and made to order with many finished options available. As a result, please expect a six week manufacturing lead time for standard specifications. Some specifications or configurations, such as tetrodes, can take an additional two to three weeks. Your Plexon Sales Engineer is happy to provide additional information and to assist you in determining what might be the most advantageous U-Probe configuration.